Single DNA Molecule Reaction Based On Dip-pen Nanolithography
نویسندگان
چکیده
منابع مشابه
"Dip-Pen" nanolithography
A direct-write "dip-pen" nanolithography (DPN) has been developed to deliver collections of molecules in a positive printing mode. An atomic force microscope (AFM) tip is used to write alkanethiols with 30-nanometer linewidth resolution on a gold thin film in a manner analogous to that of a dip pen. Molecules are delivered from the AFM tip to a solid substrate of interest via capillary transpor...
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In recent years, SPM-based lithography has attracted great attention because of its simplicity and precise control of the structure and location. Many SPM lithography techniques based on mechanical scratching,1 anodization of Si surfaces,2 electrochemical decomposition of self-assembled monolayers,3 electric field-induced chemical reactions,4 electrochemical reactions in solution using electroc...
متن کامل"Dip-Pen" nanolithography on semiconductor surfaces.
Dip-Pen Nanolithography (DPN) uses an AFM tip to deposit organic molecules through a meniscus onto an underlying substrate under ambient conditions. Thus far, the methodology has been developed exclusively for gold using alkyl or aryl thiols as inks. This study describes the first application of DPN to write organic patterns with sub-100 nm dimensions directly onto two different semiconductor s...
متن کاملDip-pen nanolithography of electrical contacts to single graphene flakes.
This study evaluates an alternative to electron-beam lithography for fabricating nanoscale graphene devices. Dip-pen nanolithography is used for defining monolayer graphene flakes and for patterning of gold electrodes through writing of an alkylthiol on thin films of gold evaporated onto graphene flakes. A wet gold etching step was used to form the individual devices. The sheet resistances of t...
متن کاملDip pen nanolithography functionalized electrical gaps for multiplexed DNA detection.
Nanoparticle-based, silver-enhanced DNA electrical detection shows great promise for point-of-care diagnostics. In this paper, we demonstrate that the dip pen nanolithography (DPN) method can be used to precisely functionalize multiple electrical gaps for multiplexed DNA detection. With the use of the DPN technique, capture ssDNAs are written inside 5 microm x 10 microm electrical gaps on subst...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2009
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2008.12.2028